To be going so far across the world again, there are just some things you have to prepare for. Once you have decided when you are traveling, check any possible school holidays and public holidays in the country(s) you are going to. It can make a lot of difference, especially the cost of some accommodation during these times.You may suddenly find a severe lack of places to stay, especially during the summer.
Of course this also depends on what sort of accommodation you aspire to. I personally don't like much below 3 stars, and we often make a few bookings which are self-catering. It gives you a base, and if you choose well, for the area(s) you will be visiting, then the daily trips can be quite easy. Secondly, with a well-equipped kitchen, you can visit a supermarket, and provide yourself with some good meals, without having to fork out for expensive dinners at restaurants.
There is also the bonus of being able to have a couple of drinks and not having to drive.
One other thing you have to do is organise the payment of your regular bills which will come up whilst you're away. There will be a few, especially if you are away for some months.
Money is also important, and you can always get some currency of the country you are visiting, but try and wait until the exchange rates are favourable.
Next, more accommodation...